Science researchers directed by King’s College London, Karolinska Institute, and Erasmus University have discovered 10 new genes that are connected to hearing loss and detected which areas of the ear were affected by them.
In June 2022, this discovery was published in The American Journal of Human Genetics. As a result, it created some skepticism about current knowledge on the origins of age-related hearing loss that stems from sensory hair cells. Based on their findings, researchers strongly believe that the stria vascularis, an area of the cochlea - which is located in the ear, is a new area of focus for treatments that help individuals with hearing loss.
Due to various factors, many people experience hearing loss as they age. By 2050, about 2.4 billion people will have some range of hearing loss. Age-related hearing problems are one of the primary chronic disabilities. It’s also a high-risk factor for dementia.
This group of researchers also reviewed genetic analyses that were made by different centers across the globe. They used samples from 723,266 patients in 17 studies who were clinically diagnosed or self-reported hearing impairment. This is currently one of the largest studies conducted on the genetic factors of hearing health. The researchers found 48 genes connected to hearing loss, including 10 new variants that are recently related to hearing.
This discovery identified genes that can be focused on for screening purposes, developing drugs, and gene therapy. It’s a secure foundation to help improve therapies against hearing loss.
If you or a loved one are experiencing hearing loss and believe hearing aids may be beneficial, please contact us at Pure Sound Hearing for a complimentary hearing test and consultation.